The threshold for those eligible to take cholesterol-lowering statins
has been drastically cut by medicines regulator the National Institute
of Health and Care Excellence (NICE), meaning millions more adults in
England, Wales and Northern Ireland will now be offered statins by
doctors.
Under controversial guidelines from the watchdog, most men aged over
60 and women over 65 will now be advised to take statins such as
Atorvastatin, Pravastatin
or Rosuvastatin. This will be the case even if they are only at a one
in 10 risk of developing cardiovascular disease. The current threshold
is 20%.
NICE say the recommendation to take
statins to an extra 4.5 million adults is necessary to avoid “a tragedy
waiting to happen” by decreasing the numbers of people suffering with
heart attacks and strokes.
Around 12.5 million people are currently eligible for the drugs, and
the NHS could see costs of an extra £52 million annually from the extra
4.5 million patients being offered statin medication. Due to decreasing
costs for the drugs, the total NHS bill for statins would actually still
be less than what it was in 2012.
Speaking yesterday, the NICE guidance panel argued the
recommendations were devised from the “biggest ever clinical trial” and
that 50,000 lives could be saved each year if those now eligible
regularly took statins.
However, that indeed could be one major stumbling block – getting
patients to keep taking their treatment. NICE admit that statin uptake
only stands at around 60% usually, and that benefits to be gained are
more likely to be 4,000 lives saved each year in addition to 22,000
strokes and heart attacks averted.
One in three deaths in the UK are the result of cardiovascular
disease. It is for this reason why statins remain the most prescribed
type of medication on the NHS, with Medical Specialists™ Pharmacy also
seeing massive amounts of patients requesting statins to help lower
their ‘bad’ LDL cholesterol, whilst raising the ‘good’ HDL cholesterol!
Although some doctors have claimed the new guidelines for statins are
primarily based on studies funded by the pharmaceutical industry, this
has been quickly refuted by NICE.
Professor Mark Baker, director of the Centre for Clinical Practice at NICE, blasted that such claims were “ludicrous”.
“Nobody gets onto our guideline groups if they have any significant
vested interest, especially a financial interest,” he commented.
“Statins are safe and effective and it is a good deal for more people to
have access to them under the NHS.”
Professor Peter Weissberg, the medical director at the British Heart
Foundation, stressed the importance of positive lifestyle choices in
lowering the risk of cardiovascular disease. He said: “Doctors will now
be able to offer a statin to people at a lower risk, but their
prescription is not mandated.
“Just as important is the emphasis on trying lifestyle changes before considering treatments with drugs.”
For example, lifestyle changes hinted at by Professor Weissberg include: quitting smoking,
maintain a healthy weight, exercise regularly, consume alcohol only in
moderation, manage stress levels better, have a diet rich in fruit and
vegetables/limited in trans fats and keep your blood pressure under
control.
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