The results from animal studies suggest that asthma treatment may bizzarely come in the form a diet rich in fruit and vegetables.
Tests on mice, as reported in the journal Nature Medicine, has found that a high-fibre diet can
impact the balance of microbes in the gut and make airways either more
or less susceptible to the inflammation involved in allergic airway
conditions such as asthma.
Asthma is a long-term respiratory
disorder, where the air passages within the lungs unexpectedly become
inflamed, narrowed, and swollen. This then prevents airflow into and out
of the lungs. Attacks often occur in response to an allergen, cold air,
exercise, or emotional stress. It is these triggers which create an
inflammatory cascade in the bronchial tree.
The last three decades have witnessed a surge in rates of
allergy-triggered asthma, in particularly in the more developed nations.
Many health experts have attributed this to changes in dietary habits,
such as a decrease in our fibre intake.
The reported stated: “In recent decades, there has been a
well-documented increase in the incidence of allergic asthma in
developed countries and coincident with this increase have been changes
in diet, including reduced consumption of fibre.”
Therefore, Dr Benjamin Marsland of the University Hospital of
Lausanne in Switzerland and colleagues, decided to study the variations
in the immune and inflammatory responses of mice when the amount of
fibre in their diet changed.
They discovered that those mice on a low-fibre diet experienced more
lung inflammation after coming into contact with dust mites. In
comparison, mice given food enriched with pectin – found in cell walls
of plants – suffered with less allergic airway problems.
It was established that this boost in soluble fibre – most often
contained in fruit and vegetables – was converted into short-chain fatty
acids. These fatty acids increase resistance to irritation in the
immune system.
For those who may struggle to adapt their diet to include more fibre,
the researchers say that a fatty acid supplement may be instead taken
to ease asthma symptoms.
Dr Marsland, spoke to BBC News, saying: “There’s a very high
probability it works in humans, the basic principle of fibre being
converted to short-chain fatty acids is known. But we don’t know what
amount of fibre would be needed and the concentrations of short-chain
fatty acids required might be different. It is early days, but the
implications could be far reaching…Moreover, these data can be
interpreted within the context of epidemiological studies showing as
fibre content in the diet has decreased, the incidence of allergies has
increased. Taken together, our findings support the concept intervention
strategies targeting diet are a valuable approach for not only
intestinal diseases but also respiratory inflammatory diseases.”
It would be foolish though to suggest asthma sufferers should disregard their blue reliever and brown preventer asthma inhalers
just yet and merely rely on consuming more fibre. A diet rich in fibre
may well be beneficial for asthmatics but it is generally recommended
for everybody as it can to help to lower cholesterol, decrease the risk
of heart disease and lessen the risk of some types of cancer.
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