If somebody says the phrase ‘erectile dysfunction’ (ED) or ‘male impotence’, one may instantly think of Pfizer’s wonder drug Viagra. This is mainly because Viagra was the very first oral medication approved for the treatment of erectile dysfunction.
The brand name Viagra will probably always be strongly associated
with ED/male impotence and its name alone carries a lot of history and
weight behind it. The active ingredient of Viagra ‘sildenafil’ will
probably not invoke the same level of familiarity and this chemical name
could sound less attractive to men. However, when it boils down to it,
that is all Viagra is – sildenafil.
Viagra’s origins are surprisingly traced
all the way back to 1989 when a group of pharmaceutical chemists working
at Pfizer’s Sandwich, Kent research facility in England, first
synthesised sildenafil citrate, a compound that they had high hopes for
in the treatment of heart problems such as angina. Two separate Phase 1
trials in addition to one Phase 2 clinical trial over the period of 1991
– 1992 revealed rather unconvincing results for angina treatment, but
it became apparent the drug’s strengths lay elsewhere.
By 1994, Pfizer researchers Nicholas Terrett and Peter Ellis noted
that men involved in the trial studies of sildenafil citrate as a heart
medicine had benefited from increased blood flow into the penis area,
aiding those who may previously had difficulty in achieving or
sustaining an erection. Over the following three years there were a
total of 21 clinical trials conducted, involving nearly 4,500 men.
Terrett and Ellis were able to prove sildenafil was both safe and
effective as a treatment for erectile dysfunction.
In 1997 the U.S. Food and Drug Administration (FDA) agreed to
give Pfizer’s ‘Viagra’ as it was now to be called, a priority review.
This is only allocated for drugs which demonstrate large advances in
treatment or can be used for a medical need. It was then approved on 27th March 1998 by the FDA and later given the go-ahead for immediate sale in the European Union in September of the same year.
The popularity of Viagra soon skyrocketed and netted its manufacturer
Pfizer billions of dollars each year, even infamously being endorsed in
TV adverts by former United States Senator Bob Dole and the Brazilian
former world cup winner and football star Pelé. The stigma surrounding
men suffering with impotence was finally starting to disappear as men
around the world embraced this revolutionary new drug which garnered
nicknames such as ‘Vitamin V’, ‘The Little Blue Pill’ and ‘Blue
Diamond’.
Men who previously kept their bedroom problems strictly in the
bedroom were now willing to discuss this genuine health problem and the
fact it is something which can cause deep distress, depression, low
self-esteem and can impact relationships. Soon even celebrity figures
such as Playboy founder Hugh Hefner were speaking of Viagra’s prowess,
with the aging lothario describing Viagra as “God’s little helper”,
whilst actor Michael Douglas, married to Catherine Zeta-Jones, raved
that Viagra was “a wonderful enhancement . . .that can make us all feel
younger.”
This takes us to the present day. Pfizer has seen its market share
dramatically decrease in the intervening years due to the entry of Eli Lilly’s Cialis and Bayer’s Levitra
and men now have more options available than ever, including the Cialis
Daily and Levitra ODT (Orodispersible) variations which have
subsequently been introduced. Medical Specialists Pharmacy is one of the
leaders in erectile dysfunction treatment and we always have our finger
on the pulse regarding the latest treatments for erectile dysfunction
and a whole host of other medical conditions.
In fact, if you are not already aware, Pfizer’s UK Viagra patent
expired on 21st June 2013 and this now makes it eligible for other
pharmaceutical companies to produce an erectile dysfunction medication
that contains sildenafil, just like Viagra. This is known as a ‘generic’
alternative. Generic medicines are known for their hugely competitive
prices which could prove a massive relief for many of us suffering from
the credit crunch-induced hardship.
For some, it is all in the name. Viagra is associated with being the
first, and thus best. But let’s not forget what it is actually inside a
Viagra tablet – sildenafil. It could be a blue diamond-shaped tablet or
a white oval-shaped tablet, regardless of its outer appearance, the
sildenafil contained inside is exactly the same and has the same purpose
– to help men suffering from erectile dysfunction to achieve and
maintain an erection that is satisfactory for sex.
For more information about the latest erectile dysfunction treatments obtainable from Medical Specialists, visit the male impotence area of the website where we have recently added new treatments such as Sildenafil Teva and Sildenafil Actavis
– both at incredibly low prices. Or, if you find tablets difficult to
swallow, we also now offer Nipatra (sildenafil) chewable tablets.
Very useful description provide about Erectile Dysfunction treatment in mens.
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