Showing posts with label orlistat. Show all posts
Showing posts with label orlistat. Show all posts

Monday, 4 July 2016

Obesity crisis means 40 million Brits could be overweight by the year 2035

Future generations could be faced with severe health problems and shorter lifespans if action is not taken now to tackle an obesity crisis that is threatening to spiral out of control, according to a new report.

The Obesity Health Alliance has estimated that about 40 million adults in the UK could be classed as overweight or obese within 2 decades, with over 7.6 million new cases of disease by 2035. Being overweight is defined as having a body mass index (BMI) of between 25 and 29.9, whilst obese is defined as having a BMI of 30 or more.

Widespread weight gain in Brits may result in 4.62 million cases of type 2 diabetes, 1.63 million cases of coronary heart disease, and 670,000 new cases of cancer, warned the new study.

This isn’t even taking into account other major health issues that can arise from piling on the pounds, not including conditions such as high blood pressure (hypertension), liver disease, osteoarthritis, or chronic kidney disease, which can all plain a huge burden on already stretched NHS resources.
Furthermore, becoming obese may then ignite other issues like poor and unhealthy eating, low self-esteem and mental health problems.

However, with swift action, a small change now could make a big difference in the future. Even just a 1% change in the number of people gaining weight every year up until 2035 may avoid around 77,000 cases of disease including 45,000 cases of type 2 diabetes in the year 2035 alone.

Therefore, the Obesity Health Alliance is urging the Government to create a substantial childhood obesity strategy immediately to combat the obesity epidemic. Measures the group want introducing include a restriction on junk food TV advertising prior to the 9pm watershed, tightening online marketing to align with broadcast regulations, as well as setting targets for industry to reduce the amount of sugar and fat in food.

Alison Cox, Cancer Research UK’s director of prevention and member the Obesity Health Alliance, said: “These numbers are shocking. And it’s difficult to think of the impact this will have on public health and an already strained NHS. Without bold action, the next generation will face more disease and live shorter lives.

“Kids are bombarded with advertisements for unhealthy food and if we are to give our children the chance for better and healthier lives, it’s vital the Government’s childhood obesity strategy restricts this kind of marketing.”

Modi Mwatsama, Director of Policy and Global Health at the UK Health Forum and member of the Obesity Health Alliance, said: “This study is a wakeup call for the Government and shows a daunting future if no strong action is taken against the obesity epidemic.
“We can’t expect industry to make changes on their own and people need help making healthier choices. Companies will have to be held accountable by Government. The Government must lead the way by creating a level playing field with independent, regulated targets for reducing the amount of sugar, fat and salt in food. Without Government action, our children face a life of disease and early death.”
According to the European Association for the Study of Obesity, here are some key facts to remember about it:
  • Worldwide obesity has nearly doubled since 1980.
  • In 2008, more than 1.4 billion adults, 20 and older, were overweight. Of these over 200 million men and nearly 300 million women were obese.
  • 35% of adults aged 20 and over were overweight in 2008, and 11% were obese.
  • 65% of the world’s population live in countries where overweight and obesity kills more people than underweight.
  • Overweight and obesity are the fifth leading risk for global deaths. At least 2.8 million adults die each year as a result of being overweight or obese.
  • 44% of the diabetes burden, 23% of the ischaemic heart disease burden and between 7% and 41% of certain cancer burdens are attributable to overweight and obesity.
  • More than 40 million children under the age of five were overweight in 2011.
  • Obesity is preventable.
Obesity will not just happen to somebody overnight. It is something that develops gradually over time, mainly due to poor diet and lifestyle choices.

NHS choices have listed the main dietary pitfalls that cause people to gain weight, which include:
  • Eating large amounts of processed or fast food – that’s high in fat and sugar.
  • Drinking too much alcohol – alcohol contains a lot of calories, and people who drink heavily are often overweight.
  • Dating out a lot – you may be tempted to also have a starter or dessert in a restaurant, and the food can be higher in fat and sugar.
  • Eating larger portions than you need – you may be encouraged to eat too much if your friends or relatives are also eating large portions.
  • Drinking too many sugary drinks – including soft drinks and fruit juice.
  • Comfort eating – if you have low self-esteem or feel depressed, you may eat to make yourself feel better.
Lack of physical activity is a key factor behind obesity, with many using their cars to get around and doing less walking or cycling. Moreover, we are becoming a nation of TV and computer game addicts, instead of getting out and doing regular exercise.


The Department of Health recommends that each week adults should be engaging in at least 150 minutes (2 and a half hours) of moderate-intensity aerobic activity, such as cycling or fast walking. However, this doesn’t need to be done all in one go. For example, you could exercise for 30 minutes a day for 5 days in the week.

Medical Specialists® Pharmacy are able to provide help for those trying to lose weight, with our fantastic range of obesity treatments such as Xenical and Orlistat. Used in conjunction with a balanced diet and exercise, these treatments are very effective in enabling people to lose weight and regain confidence again.

Friday, 23 January 2015

National Obesity Awareness Week 2015 encourages small changes now for long-term gains

Monday saw the beginning of National Obesity Awareness Week 2015, a campaign that aims to take back control of the nation’s spiralling obesity crisis, and, as many of us will have ‘weight loss’ as one of our New Year’s resolutions, there is no better time to act than now.

Alarmingly, around 25% of adults are deemed to be obese. According to NHS Choices, a BMI of 30 to 39.9 means you are considered obese, and the government claims that unless the problem is tackled, 60% of men, 50% of women and 24% of children will be obese by the year 2050.

Clearly, obesity is an incredibly serious problem that needs fighting. It effects not only our personal health – increasing the risk of problems including heart attacks, stroke, cancer, type 2 diabetes and arthritis – but can have a detrimental impact to society.

McKinsey and Company produced a report last year documenting the country’s various yearly outgoings, with their economic analysis estimating that the fight against obesity is costing the UK even more than tackling armed violence, war and terrorism. According to their calculations, the problem of obesity costs the UK in excess of £46.5bn ($73bn) a year, in comparison to the £43bn ($67bn) it costs the country due to armed violence, war and terrorism. The biggest social cost to the country though – and by some distance – remains smoking, with the impact from smoking costing a staggering £57bn ($86bn) in 2012.

On a global scale, armed violence, war and terrorism is costing the economy $2.1 trillion a year, and obesity isn’t too far behind, at $2 trillion, with the following social burden being alcoholism, costing $1.4 trillion.

Unfortunately, obesity appears to be a growing problem. Almost a quarter of children are considered to be obese upon leaving primary school, in addition to the one in four adults also obese. Over 12,000 hospital appointments are made each year because of health issues associated with obesity, placing further pressure on an already stretched NHS budget.

However, this is where National Obesity Awareness Week comes into play, aiming to promote the various methods how the government, businesses and us as individuals can implement positive steps to boost our health, with the information and resources from the campaign enabling a long-term positive change. This doesn’t mean people have to make astronomical alterations, but smaller, manageable and sustainable changes that can be kept up beyond National Obesity Awareness Week – this might be cutting down on sugar in your diet, reducing alcohol intake, or increasing the amount of exercise you do.


The campaign encourages everyone to get involved, whether it is events, activities and promotions taking place around the country, or people can even organise their own event with the online supporters’ pack.

The National Obesity Awareness Week website is also full of fantastic, useful information, such as exercise tips to help successful weight loss, an explanation of calories and the number of calories expended in an hour of doing various exercise such as running or swimming, why low-fat diets don’t always work for those trying to lose weight, healthier cooking recipes, a breakdown of the vitamins and minerals we need in our diets and their purposes, how to stay active during pregnancy and much more.


So, whatever it is you decide to do to take part, why don’t we all commit to making 2015 the year we take action with manageable and sustainable changes to turn the obesity crisis around before it is too late.

Medical Specialists® Pharmacy can also help those trying to lose weight, with our fantastic range of obesity treatments such as Xenical and Orlistat. Used in conjunction with a balanced diet and exercise, these treatments are very effective and can help people regain their confidence to enjoy a happier and healthier 2015!

Tuesday, 23 December 2014

Scientists develop obesity pill to ‘replace treadmill’

With Christmas Day now just a fortnight away, it would not be a surprise if much of the population found their pants becoming ever so tighter in the coming weeks, as the high calorie content of festive treats like mince pies, Christmas pudding and novelty chocolate foods start to creep onto the waistline.

To further show this point, a 2011 survey conducted by MSN found that the average Brit will consume two or three Christmas dinner servings on the day itself, taking in 2,300 calories in the process. This equates to a staggering 115% of the recommended daily intake for women and 92% for men.

It seems a lot of people are worried about the extra calories and are preparing for the possibility of weight gain this year as Medical Specialists® Pharmacy have seen a massive surge in the number of people coming to them seeking help with losing weight and enquiring about the obesity treatments available such as Xenical and Orlistat. Medical Specialists® have also witnessed a huge increase in requests for treatment for conditions usually worsened by the cold weather such as influenza and asthma.

However, it is still weight gain that remains as the primary worry for much of the nation over the festive period, but there has been good news this week for those trying to lose weight. It has emerged that scientists in America are developing a pill that could help the body to burn off excess fat and its creators even claim that “it could one day replace the treadmill”.

Researchers based at Harvard University have found a way to trigger a molecule that can convert ‘bad’ white fat cells into ‘good’ brown cells that help to burn energy.

When a person consumes too many calories and doesn’t burn off a sufficient amount, adult stem cells in the body start to generate a higher amount of white fat cells, leading to a flabbier physique, especially evident around the stomach and hips.

Brown fat cells on the other hand, are used by the body to burn energy and produce heat. The colder the body becomes, the higher amount of brown fat cells begin to get used up, and hence they are generally easier to get rid of compared to the white cells. Not only this, but the brown cells also work to reduce both the size and numbers of their white counterparts.

Researchers say they have managed to pinpoint which molecule is responsible for turning stem cells white or brown, and state that by increasing the molecule, this will help the body to generate more brown cells, instead of white.

Associate professor Chad Cowan, at Harvard, said: “What we were really impressed by is that there are some compounds that have this same kind of effect when they are administered to animals, but when you remove them, the effect goes away.

“But what we saw here was a stable conversion of the white fat cells to brown cells. You’re constantly replenishing your fat tissue so if you were on a medication to convert the cells, each new fat cell would be more metabolically active and would convert to brown fat over time.”

The scientists involved with the research go on to claim that this decreases the risk of a person developing health conditions associated with a fat build-up, such as type 2 diabetes.

A drug called tofacitinib, which helps to trigger the molecule for cell conversion is actually already approved, but for the treatment of rheumatoid arthritis. However, it remains to be seen exactly when a pill for obesity that contains the molecule will be approved, with fears it could damage the immune system.

Professor Cowan warned the compounds “target the same molecule, and that molecule plays a role in the inflammatory response”.

He stressed: “So if you administered them for a long time, the person taking them could become immune compromised”, and his team added that despite the fact any future obesity pill may help people to remain trim, it would still not be a sufficient substitute for the other health benefits to be gained from engaging in regular exercise.

Thursday, 13 September 2012

Can new weight loss drugs rival Xenical


Recently, the American Food and Drug Administration (FDA), approved two new weight loss medications (Belviq and Qysmia), and America breathed a sigh of relief. While weight loss drugs have always been a topic of controversy, over the years it has become clear that their addition to the dieting efforts of many individuals, who struggle with obesity, is extremely beneficial. And with more than one third of Americans (35.7%) falling under the obese category, it is no surprise that medical alternatives to diet and exercise, are needed to counteract the issue.
New obesity treatments are needed to bridge the gap between diet and exercise and the more radical option of bariatric surgery. This is a view backed up by Dr Sue DeCotiis, New York City based Medical Internist and Weight Loss Management Specialist, who said, “While there are potential side effects with every medication, long term studies show that overweight patients do much better losing and keeping off weight, when they are prescribed a weight loss drug.”
“Weight loss medications work in conjunction with healthy eating and exercise, and offer individuals a chance at a real lifestyle change. Those who suffer from obesity often have a host of other health problems that come with the condition. These drugs can alleviate those symptoms, and the result is that many of these patients will live longer and avoid the consequences of medical problems, such as hypertension, stroke, and heart attack.”
Listed below is a description of current weight loss drugs and how they work. Previously the only option was Xenical, but now for the first time in 13 years, Doctors will have a choice of which weight loss drugs to prescribe to overweight or obese patients.
Belviq (Locaserin)
Approved by the FDA in late June of this year, this medication works by activating a receptor in the brain that helps a person to eat less and still feel full. By regulating the appetite, it lowers the likelihood of individuals overeating. It works best in patients who suffer from weight related conditions, such as high blood pressure, type 2 diabetes, or high cholesterol. At least 47.5% of patients lost at least 5% of their body weight from the medication, as opposed to 20.3% who took a placebo during a trial study period.
Qsymia (Phentermine & Topirmate)
This combination of the drugs Phentermine (an appetite suppressant and stimulant) and Topirmate (an anticonvulsant with weight loss side effects) is the most recent of the crop of weight loss medications, that have been approved by the FDA. Drugs in this category are primarily considered appetite suppressants. With the medication producing dramatic weight loss in patients, this is one of the clearest signs of hope for those suffering from obesity related diseases. About half of the patients lost 10% of their body weight and four-fifths lost 5%.
Contrave (Bupropion & Naltrexone)
This drug that is still to be approved by the FDA, works by combining two active ingredients that have been used for over twenty years. With Bupropion initiating the weight loss, Naltrexone sustains it by preventing the body’s natural tendency to counteract efforts, to lose weight. The result of this combination is to reduce appetite and increase the body’s metabolism, giving those who are suffering from obesity related illnesses the ability to sustain continued weight loss, by addressing the portion of the brain that controls food cravings.
Xenical (Orlistat)
Xenical, which is the most established and proven of the weight loss drugs, is a lipase inhibitor. Xenical does not enter the patient’s blood stream, but works in the digestive system in the small intestine as a fat absorber. It blocks out a third of the fat in food eaten in a patient’s diet, leading to steady weight loss. Research involving 11,131 woman and 4,418 men, who had been over weight for an average of 14 years, showed that 87% lost at least 5% of total body weight, half lost at least 10%, around 20% lost more than 15% body weight and some patients lost more than 25%.
Only time will tell which of these weight loss drugs is the most successful. Unfortunately here in the UK Belviq is not expected to be released until 2013 and there has been no UK release date as yet for Qsymia and Contrave. However all is not lost as here in the UK we still have Xenical available, which has a proven track record for assisting weight loss. Here at Medical Specialists Pharmacy we can dispense Xenical after an online consultation with one of our doctors and as soon as these other weight loss drugs become available, we will be offering them. Check our news section for further updates.