Cialis daily could help men with ED return to normal erectile function

The results of a new study published in the Journal of Sexual Medicine show that men with an ‘incomplete response’ to an as-needed PDE5 inhibitor treatment for impotence, achieved normal erectile function after taking a course of Cialis (Tadalafil) once daily treatment – via measurement on the erectile function domain of the International Index of Erectile Function (IIEF-EF). This is a series of questions used as a measure for efficacy assessment in erectile dysfunction clinical trials, first developed in conjunction with the clinical trial program for sildenafil.

Cialis belongs to a class of drugs known as a ‘Phosphodiesterase-5 (PDE-5) inhibitor’, first approved to treat erectile dysfunction (ED) and then for the signs and symptoms of benign prostatic hyperplasia (BPH).

“PDE5 inhibitors are highly effective for most men when taken as-needed, but responses can range from minimal change to a return to normal erectile function,” said Dr Edward D. Kim, MD, of the Division of Urology, Department of Surgery, University of Tennessee Graduate School of Medicine and lead author of the study. “We believe the study outcome will help prescribers make better informed decisions when treating their patients.”

The study was a randomised, double-blind, parallel, placebo-controlled trial that encompassed 51 sites from the United States and Canada. Participants in the study were men 18-years-old or over who had taken an as-need PDE5 inhibitor at maximum dose and achieved some response to the treatment (IIEF-EF >/= 17), however had not managed to experience a normal erectile function (IIEF-EF <26 p="">
Researchers analysed the superiority of the Cialis daily treatment to that of a placebo in helping the men get back to a normal erectile function. There were a total of 623 subjects randomly assigned to receive Cialis as a once daily treatment, or given the ineffective placebo.

A primary objective of the study was to determine if a significantly greater percentage of the men returned to normal erectile function when given Cialis 2.5 titrated to 5 mg and 5 mg once daily, in comparison to a placebo.

Treatment with the Cialis daily in this matter met the primary objective with significantly higher percentages of men (38.7 percent and 39.6 percent, respectively) with IIEF-EF domain scores in the normal range (>/= 26) through 12 weeks versus the placebo (12.1 percent; both, p<.001).

By the fourth week of assessment, significantly higher percentages of men taking the Cialis 2.5 to 5 mg and 5 mg (33.5 percent and 41.1 percent, respectively) had successfully returned to normal erectile function (placebo, 8.5 percent; both, p<.001).

The study highlights the prowess of Cialis daily for the treatment of erectile dysfunction. Cialis vs Viagra  is a difficult choice for many, but it is worth bearing in mind that the lower strength versions of Cialis are particularly ideally for men in sexually active long-term relationships. Beneficial in that the mild dose will be in your body each day, it means you do not have to take a tablet each time you have sex. Your body should begin to adjust to the medication’s ingredients and resulting in very little side effects, if any.

ED drug Cialis helps ejaculation and orgasm problems too

The findings of a new U.S. based study published within the February edition of the British Journal of Urology International suggests that the wonder erectile dysfunction medication (ED) Cialis may provide use to men in other areas of sexual dysfunction besides the obvious one of helping them to achieve and maintain an erection.

According to those behind the study, non-erectile sexual dysfunction issues are often both underreported and undertreated compared to ED possible due to a social stigma involved in addition to confusion about the physiology of male sexual response and orgasmic dysfunction, but problems reaching an orgasm and ejaculating are actually more common that people realise.

‘The Weekend Pill’ Cialis is one of three main ED medications together with Viagra and Levitra, rapidly becoming popular with millions of men after stepping out of large shadow cast by Viagra purely because it was released before Cialis and Levitra.

In recent times as clinical trials have taken place exploring the massive potential of Cialis, it has received European approval to be prescribed to men suffering with both ED and benign prostatic hyperplasia (BPH); a condition that mainly affects older men that results in an enlarged prostate gland and problems including difficulty passing urine, a need to urinate frequently, or finding it difficult to completely empty the bladder.

Researchers from NewYork-Presbyterian Hospital/Weill Cornell Medical Center, led by Dr. Darius Paduch, opted for a meta-analysis statistical analysis – examining data extracted from 17 different placebo-controlled clinical trials that included a total of 3,581 participants, with a mean age of 54.9. Only some of the patients had reported as having mild or moderate ED.

In total, it was calculated that 1,512 of the men were suffering with severe ejaculatory dysfunction (EJD) and 1,812 had severe orgasmic dysfunction (OD) – two closely linked conditions but slightly different in that men with EJD experience an inability to achieve ejaculation during sexual activity, despite the male wanting to and still having an erection. OD is also referred to as ‘Anorgasmia’, whereby there is a loss of ability to have an orgasm which could be connected to factors such as certain medications, illness, depression, alcoholism or pelvic surgery. ‘Primary anorgasmia’ sufferers however have never achieved an orgasm despite sexual activity, but this is more prevalent in women.

The researchers looked at the men’s response to questions about what (if any) impact that Cialis had on ED, EJD, and OD, among other measures of sexual satisfaction. The questionnaire was tailored more towards ED and how Cialis improved this, but the comments given by the participants were intriguing and showed that Cialis could be used in other areas of sexual dysfunction too.

After a meta-analysis of the clinical trials, it was found that 66% of men who had severe EJD and 66% with severe OD who took Cialis prior to sexual activity over 12 weeks reported improved ejaculatory function, compared to just 36% and 35%, respectively, in the group assigned the placebo. Interestingly, benefits from Cialis were evident regardless of severity of the man’s ED.

Speaking in a press release, Dr Paduch said: “There are many men who have, at most, very mild problems achieving an erection but who cannot easily ejaculate. Our study shows Cialis works very well for these men with problems ejaculating. Many of my patients are young men who want to have children and so they want to solve their issues with ejaculation. We don’t know why this occurs. Every internist faces this problem in his male patients and has no options to offer. Our study shows Cialis may help.”

Daily fizzy drink intake linked to aggressive prostate cancer

As if there weren’t enough reasons to give-up sugary fizzy drinks, a new Swedish study has perhaps added another persuader to this. In addition to helping to rot teeth and adding extra inches to your waistline due to the massive sugar content, there have been studies to emerge this year that have found that fizzy drinks can have even more detrimental effects to health. For instance, in February it was revealed in an Australian study that soft drinks could result in an increased danger of developing asthma or chronic obstructive pulmonary disease (COPD).


Then in June, high levels of the dangerous colouring agent 4-methylimidazole (4-MI)  were found in cans of Coca-Cola in numerous countries around the world, a chemical shown in tests to be connected to cancer within some animals. Past research has also linked brittle bones, heart attacks, diabetes, pancreatic cancer, muscle weakness and even paralysis as possible dangers from the long-term heavy consumption of such drinks.

The new study, conducted by scientists at Lund University in Sweden, has found evidence that shows men who consume just one solitary 300ml soft drink each day  - less than a standard 330ml can – could be at a 40% higher risk at developing serious forms of prostate cancer; the most prevalent type of cancer in UK males. This is in comparison to men who refrain from drinking soft drinks.
Prostate cancer develops in the prostate – a gland in the male reproductive system. In the UK alone there are an estimated 36,000 to 40,000 men who are diagnosed with prostate cancer and there are about 250,000 men currently living with the disease. It tragically claims the lives of over 10,000 men in the UK every year.

The Swedish study involved tracking 8,000 healthy men who were aged between 45 to 73 years of age for an average of around 15 years.  All the men were in perfect health at the beginning of the study and were continually quizzed about their dietary preferences, including soft drink intake.
At the close of the study, the researchers compared the diets of the men who had been diagnosed with prostate cancer against that of the healthy men, and subsequently established a link between intake of sugary drinks and the potentially fatal disease.

Isabel Drake, Lund University researcher, commented on the study findings and said: “Among the men who drank a lot of soft drinks we saw an increased risk of prostate cancer of around 40 per cent.”
Their investigation also established some link between a less severe type of prostate cancer and large amounts of rice and pasta, cakes and biscuits, and sugary breakfast cereals that were in the subject’s diet.

However, before people start to panic and banish these foods from their diet completely, Dr Iain Frame, director of research at Prostate Cancer UK, attempted urged caution in interpreting the study findings and said:  “We cannot be certain whether any particular dietary pattern has a significant impact on a man’s risk of getting prostate cancer but it is highly unlikely that any single food source will lead to an increased chance of developing the disease.” In addition, Drake also stressed that more research would be required to fully prove any definite links between dietary choices and prostate cancer.

Symptoms of prostate cancer include: having to urinate more frequently, difficulty beginning to urinate, a feeling that your bladder has not been fully emptied and a weak flow of urine. If you are suffering with any symptoms similar to these you should visit your own GP as soon as possible for a check-up. The earlier prostate cancer is spotted – the better chance of treatment being effective and a full recovery can be made. If it is not prostate cancer then you may be one of 2.4 million men in the UK suffering from a condition called benign prostatic hyperplasia. Also known as an enlarged prostate gland, it can be treated through the use of effective medication such as Flomax Relief, which eases the symptoms associated with lower urinary tract symptoms (LUTS) of a BPH. Flomax works by relaxing muscles in the prostate gland, relaxing the muscles in the urethra (the tube from the bladder to the outside of the body).  This allows urine to travel more comfortably through the urethra, making it easier to urinate. Flomax is available today from the Medical Specialists Pharmacy chemist shop priced at just £8.75 for 14 capsules, or £15.95 for 28.

High blood pressure and obesity increase prostate cancer mortality

Prostate cancer is the second most common cause of cancer death, after lung cancer. Just in the UK alone, it is estimated that around 36,000 men are diagnosed with prostate cancer each year and it is responsible for a quarter of all newly diagnosed cases of cancer in men. Of this total of 36,000, just under a third will tragically die; usually because it has not been identified and treated early enough.
Unfortunately, prostate cancer will usually cause no symptoms until the cancer has become big enough to place pressure on the urethra. The symptoms are also incredibly similar to benign prostatic hyperplasia, and thus if you have such symptoms, it may not automatically mean you have prostate cancer. They include: having to urinate more frequently, problems actually beginning to urinate, a feeling that your bladder has not been fully emptied and a weak flow of urine.

The older you get, the chances increase of you developing prostate cancer, with it particularly being prevalent in people over the age of 70. However, a new study has come to light that sheds more light on the ‘high-risk’ groups, and what factors contribute to the deadly cancer.

Dr Christel Haggstrom, from Umea University, Sweden, and her team assessed nearly 300,000 males from Austria, Norway and Sweden over a duration of twelve years. Their aim was to analyse prostate cancer prevalence, how many deaths occurred, and what factors were contributing to prostate cancer incidence. The study was known as ‘The Metabolic Syndrome and Cancer (MeCan) project’.

Through the follow-up period of twelve years, a total of 6,673 men developed prostate cancer and of these, 961 unfortunately died from the disease. It was discovered that those who had among the highest BMI readings, had a 36% chance of dying from prostate cancer. For those with the highest blood pressure readings, the mortality rate was calculated as 62%.

Dr Haggstrom and colleagues looked at a wide range of risk factors, including high body mass index (BMI), high blood pressure, and high levels of sugar and fats in the blood, This is collectively known as ‘metabolic syndrome’. She said: “When we looked to see if the metabolic factors are related to an increased risk of getting or dying from prostate cancer we found a relationship with death from the disease and high blood pressure. There was also a link to high BMI but blood pressure had the strongest association to increased risk. The results for BMI are in line with previous findings in large studies. I can’t speculate on the reasons for the association between having high blood pressure and dying from prostate cancer. More research is needed to find out why this is the case but the results add further evidence to the hypothesis that high levels of metabolic factors separately or combined are related to an increased risk of dying from the disease.”

Pär Stattin, MD, PhD, from the Memorial Sloan-Kettering Cancer Center in New York City, led the study. He commented on its findings, saying: “These observations suggest that cardiovascular risk factors such as overweight and hypertension are involved in stimulating the progression of prostate cancer.”

If you are suffering with any symptoms mentioned earlier, you should visit your own GP as soon as possible for a check-up and do not delay in doing this. The earlier prostate cancer is spotted – the better chance of treatment being effective and a full recovery can be made. Alternatively, there is a chance you could be one of the 2.4 million men in the UK suffering from the previously mentioned condition, benign prostatic hyperplasia. Also known as an enlarged prostate gland, it can be treated through the use of effective medication such as Flomax Relief, which eases the symptoms associated with lower urinary tract symptoms (LUTS) of a BPH. Flomax works by relaxing muscles in the prostate gland, relaxing the muscles in the urethra (the tube from the bladder to the outside of the body).  This lets urine pass more freely through the urethra, making it easier to urinate. It is available today from the Medical Specialists Pharmacy chemist shop, costing just £8.75 for 14 capsules, or £15.95 for 28.

ED drug Cialis gets European approval for benign prostatic hyperplasia

Struggling to think of a link between benign prostatic hyperplasia (BPH) and erectile dysfunction (ED)? You might not be the only one. However, patients who are suffering with both of these conditions may soon be able to be treated through the male impotence wonder drug Cialis, which it seems, is emerging as having multiple uses.

The European Union’s Committee for Medicinal Products for Human Use (CHMP) has put forth their recommendations for the approval of the 5 mg daily dose of Cialis to treat the condition BPH that can result in prostate enlargement, a common condition that usually effects older men and leads to problems including; difficulty passing urine, a regular need to urinate, or finding it difficult to completely empty the bladder.

All that waits now is a final ruling from the European Commission, who approves medicinal use for the EU. It usually takes the European Commission about one to two months to decide on CHMP recommendations. All this follows a precedent set back in October 2011 when the U.S. Food and Drug Administration (FDA) gave their seal of approval for Cialis 5 mg once daily use to be used to alleviate the signs and symptoms of BPH.

Cialis is currently used to help men suffering with ED in over 100 countries and has already been approved in many other countries around the globe for the additional purpose of helping BPH, including Argentina, Brazil, Canada, Columbia, Costa Rica, Ecuador, Honduras, Israel, Panama, Russia and South Korea. Therefore, it will surely only be a matter of time before patients can obtain Cialis Daily from Medical Specialists Pharmacy for benign prostatic hyperplasia in addition to treat erectile dysfunction. The best thing we would advise is to keep checking our website for more developments on this subject.

Anthony Beardsworth, senior medical director at Lilly, spoke on the exciting news and said, “The CHMP positive opinion for Cialis marks an important regulatory milestone for Eli Lilly and Co and our commitment to bringing new treatment options to the millions of men who experience ED and BPH.”

If you are a male suffering with urinary problems, then you may be one the 2.4 million men in the UK suffering from BPH. It could be some time yet until Cialis Daily is officially given the green light to fight such issues. In the meantime, urinary problems can be treated through the use of effective medication such as Flomax Relief, which eases the symptoms associated with lower urinary tract symptoms (LUTS) of a BPH.

Flomax works by relaxing muscles in the prostate gland, relaxing the muscles in the urethra (the tube from the bladder to the outside of the body).  This lets urine pass more freely through the urethra, making it easier to urinate. It is available today from the Medical Specialists Pharmacy chemist shop, costing just £8.75 for 14 capsules, or £15.95 for 28.

Of course if you are a male suffering with erectile dysfunction and would like to know your options in regards to treatment, you may be wondering just what ‘Cialis Daily’ is. Firstly, it is a once-daily tablet supplied in two does; 2.5 mg and 5 mg, with 28 tablets to a pack. It is recommended to be taken at the same time each day for consistency and is suitable for men who are in sexually active long-term relationships. The major benefit is that the mild dose of Tadalafil (Cialis’ active ingredient) will be in your body each day, meaning you do not have to take a tablet each time you have sex. Cialis, Cialis Daily, Levitra, Levitra ODT and Viagra are all available today at great prices through Medical Specialists.