New research suggests that adolescents who begin drinking during
puberty are at a higher risk of suffering with alcohol problems and
becoming addicted during adulthood.
A long-standing opinion amongst parents is that if they allow their
children to drink supervised at an early age then this encourages their
children to drink responsibly and have a better attitude towards alcohol
as they get older.
However, a team of researchers from the
University of Heidelberg in Germany may have now dispelled this theory
as purely a myth and that neurodevelopmental changes that occur during
puberty leave the body particularly susceptible to alcohol abuse later
in life. The researchers say they have witnessed higher drinking levels
in those who began drinking at an earlier stage.
Study co-author Miriam Schneider of the University of Heidelberg,
comments: “Most teenagers have their first alcoholic drink during
puberty; however, most research on the risks of early-onset alcohol use
up to now has not focused on the pubertal stage during which the first
alcoholic drink is consumed. Common thinking in alcohol research was
that the earlier adolescents begin, the more deleterious become their
drinking habits. However, a closer look at the statistics revealed a
peak risk of alcohol use disorders for those beginning at 12 to 14 years
of age, while even earlier beginners seemed to have a slightly lower
risk.”
The longitudinal study was comprised of 283 participants – 152
females and 131 males. Each person was quizzed at ages 19, 22, and 23,
with researchers issuing a questionnaire to calculate number of drinking
days, amount of alcohol consumed, and any possible dangerous drinking
levels. The results from a separate animal study were also used for
comparative purposes and also showed a similar pattern. This particular
study had analysed the voluntary ethanol consumption of Wistar 20 rat
subjects at puberty and as they got older.
Schneider noted: “Both studies revealed that those individuals that
initiated alcohol consumption during puberty tended to drink more and
also more frequently than those starting after puberty.”
The point at which puberty begins can vary between each person,
however Schneider was still able to observe that the stage of puberty
appears to be the time when adolescents are most vulnerable –
unsurprising considering the changes occurring in the growth and pruning
of neurons (where the brain removes neurons no longer in use or useful)
and synapses. Not only this, but puberty will cause adolescents to
experience particularly high receptivity and development in their
brain’s reward system.
Schneider continued: “Puberty is a very critical developmental period
due to on-going neurodevelopmental processes in the brain. It is
exactly during puberty that substances like drugs of abuse — alcohol,
cannabis, etc., may induce the most destructive and also persistent
effects on the still developing brain, which may in some cases even
result in neuropsychiatric disorders, such as schizophrenia or addictive
disorders. Prevention work therefore needs to increase awareness of
specific risks and vulnerability related to puberty.”
Dr Schneider’s colleague Dr Rainer Spanagel added: “Puberty is a
phase in which the brain reward system undergoes major functional
changes. Therefore, during puberty the brain is in a highly vulnerable
state for any kind of reward, and drug rewards in particular.”
Showing posts with label alcoholism. Show all posts
Showing posts with label alcoholism. Show all posts
Thursday, 23 May 2013
Thursday, 18 October 2012
German researchers claim heavy drinking can kill you sooner than smoking
According to experts in Germany, heavy boozing can send you to an
early grave and ‘kills you quicker than smoking’ they say. In
particularly, women who drink heavily are at a much greater risk of a
premature death in comparison to men.
Academics in Germany recently published their study and the subsequent startling findings in the journal Alcoholism: Clinical & Experimental Research. Professor Ulrich John, of University Medicine Greifswald and his team analysed a completely random selection of over 4,000 people between the ages of 18 and 64. From this total, 153 were identified as being alcohol dependent (AD). Of the 153, 149 were closely tracked for 14 years (119 men, 30 women).
This latest study has caused such a buzz mainly because it has assessed the impact of alcohol dependency over a longer period of time, whereas past studies have been mainly established via clinical trials to find risks associated with excessive alcohol consumption.
Professor Ulrich John explained, “Clinical data have revealed a higher proportion of individuals who have died than among the general population of the same age. Gender-specific data are rare, even among clinical samples. Furthermore, these studies have two main limitations. First, we know that only a minority of AD individuals receive treatment of this disorder, but we lack knowledge about how this selection occurs. Second, we have no evidence about potential effects of specialised alcoholism treatment on mortality among people who had been diagnosed as AD. We would like to know whether treatment might enhance survival time. For ethical reasons, no controlled trials are possible. Thus, longitudinal descriptive data as in this study are helpful.”
After the 14 years, there were some shocking findings for Professor John. He continued, “First, we found that annualised death rates were 4.6-fold higher for females and 1.9-fold higher for males compared to the age- and gender-specific general population. Second, we found that the mean age at death was 60 for females and 58 for males, both of which are about 20 years lower than the mean age at death among the general population. None of those deceased had reached the age of life expectancy. Third, having participated in inpatient AD treatment was not related with longer survival compared to not having taken part in treatment, meaning that it did not seem to have a sufficient protective effect against premature death.”
Overall the findings would seem to heavily suggest that alcohol abuse can result in more early fatalities compared to a lifetime of smoking. Professor John concluded, “Smoking-related death cases are more due to cancers which seem to occur later in life than many alcohol-attributable causes of death do. Furthermore, drinking can also contribute to other risky behaviours such as smoking, becoming overweight, and obesity. Alcohol is a dangerous product and should be consumed only within guidelines.”
If you think you have an alcohol dependency problem, Medical Specialists Pharmacy believes you should see your own GP as soon as possible. A dependency on alcohol is risked if you are regularly drinking large quantities of alcohol and find it difficult to even go through a single day without feeling like you need a drink. With many people, a high tolerance to alcohol may develop and larger amounts of alcohol than previous are needed before any effects are actually felt. By visiting your GP, they can warn you of the health dangers that your drinking is having and the resulting damage to your body that will occur if you continue down that particular path. In addition, they can offer treatment programs and get you involved in support groups or counselling. It has been proven on many occasions that alcoholics can cut down or stop drinking altogether by discussing their problems, and from the additional support of family and friends.
However, alcohol is not the only subject in this story. Medical Specialists Pharmacy is slightly concerned that people could misinterpret the findings from this particular study and now underestimate the dangers of smoking, wrongly believing it is safe to smoke. Both heavy smoking and alcohol intake are incredibly damaging to a person’s health and ideally both should be limited to an absolute minimum, or stopped altogether. In fact already this year we have discussed how smoking can contribute towards the bone disease osteoporosis, skin cancer and asthma. In addition we have recently looked in-depth at the huge hidden health risks associated with secondhand and thirdhand smoking.
Prevent the risk of developing these conditions today though with the help of Medical Specialists. Champix is a prescription medication that can be obtained following an online consultation with one of our GMC registered doctors. It works out from as little as just £75.00 per pack, an incredibly small price when it comes to your long-term health. Champix mimics the effect of nicotine on the body, reducing the urge to smoke and relieving withdrawal symptoms. It can also decrease the enjoyment you experience of smoking if you are still smoking whilst on the treatment.
Academics in Germany recently published their study and the subsequent startling findings in the journal Alcoholism: Clinical & Experimental Research. Professor Ulrich John, of University Medicine Greifswald and his team analysed a completely random selection of over 4,000 people between the ages of 18 and 64. From this total, 153 were identified as being alcohol dependent (AD). Of the 153, 149 were closely tracked for 14 years (119 men, 30 women).
This latest study has caused such a buzz mainly because it has assessed the impact of alcohol dependency over a longer period of time, whereas past studies have been mainly established via clinical trials to find risks associated with excessive alcohol consumption.
Professor Ulrich John explained, “Clinical data have revealed a higher proportion of individuals who have died than among the general population of the same age. Gender-specific data are rare, even among clinical samples. Furthermore, these studies have two main limitations. First, we know that only a minority of AD individuals receive treatment of this disorder, but we lack knowledge about how this selection occurs. Second, we have no evidence about potential effects of specialised alcoholism treatment on mortality among people who had been diagnosed as AD. We would like to know whether treatment might enhance survival time. For ethical reasons, no controlled trials are possible. Thus, longitudinal descriptive data as in this study are helpful.”
After the 14 years, there were some shocking findings for Professor John. He continued, “First, we found that annualised death rates were 4.6-fold higher for females and 1.9-fold higher for males compared to the age- and gender-specific general population. Second, we found that the mean age at death was 60 for females and 58 for males, both of which are about 20 years lower than the mean age at death among the general population. None of those deceased had reached the age of life expectancy. Third, having participated in inpatient AD treatment was not related with longer survival compared to not having taken part in treatment, meaning that it did not seem to have a sufficient protective effect against premature death.”
Overall the findings would seem to heavily suggest that alcohol abuse can result in more early fatalities compared to a lifetime of smoking. Professor John concluded, “Smoking-related death cases are more due to cancers which seem to occur later in life than many alcohol-attributable causes of death do. Furthermore, drinking can also contribute to other risky behaviours such as smoking, becoming overweight, and obesity. Alcohol is a dangerous product and should be consumed only within guidelines.”
If you think you have an alcohol dependency problem, Medical Specialists Pharmacy believes you should see your own GP as soon as possible. A dependency on alcohol is risked if you are regularly drinking large quantities of alcohol and find it difficult to even go through a single day without feeling like you need a drink. With many people, a high tolerance to alcohol may develop and larger amounts of alcohol than previous are needed before any effects are actually felt. By visiting your GP, they can warn you of the health dangers that your drinking is having and the resulting damage to your body that will occur if you continue down that particular path. In addition, they can offer treatment programs and get you involved in support groups or counselling. It has been proven on many occasions that alcoholics can cut down or stop drinking altogether by discussing their problems, and from the additional support of family and friends.
However, alcohol is not the only subject in this story. Medical Specialists Pharmacy is slightly concerned that people could misinterpret the findings from this particular study and now underestimate the dangers of smoking, wrongly believing it is safe to smoke. Both heavy smoking and alcohol intake are incredibly damaging to a person’s health and ideally both should be limited to an absolute minimum, or stopped altogether. In fact already this year we have discussed how smoking can contribute towards the bone disease osteoporosis, skin cancer and asthma. In addition we have recently looked in-depth at the huge hidden health risks associated with secondhand and thirdhand smoking.
Prevent the risk of developing these conditions today though with the help of Medical Specialists. Champix is a prescription medication that can be obtained following an online consultation with one of our GMC registered doctors. It works out from as little as just £75.00 per pack, an incredibly small price when it comes to your long-term health. Champix mimics the effect of nicotine on the body, reducing the urge to smoke and relieving withdrawal symptoms. It can also decrease the enjoyment you experience of smoking if you are still smoking whilst on the treatment.
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