Scientists say Viagra could help to tackle obesity

Erectile dysfunction (ED) medications such as Viagra and Cialis are obviously known for their potency in helping men to achieve and maintain an erection that is satisfactory for sex. It must worth bearing in mind however that Viagra was initially developed at Pfizer’s Kent research facility many years ago as a treatment therapy for hypertension (high blood pressure) and angina pectoris (a symptom of ischaemic heart disease). It was only following clinical trials it was discovered that Viagra had significant effects of erections, and ironically rather ineffective for angina treatment like first anticipated.

With this in mind, scientists over the years have long wondered if sildenafil citrate (Viagra’s active ingredient) could work at treating any other health conditions, and studies are regularly carried out to determine what other uses it may have.

In 2012 TV gardener David Domoney claimed that simply crushing a 50mg tablet up and placing just a fraction of this into the water, could dramatically increase the life of flowers. Whereas others are adamant that Viagra’s positive impact on blood flow may be taken advantage of for athletes, with evidence to suggest that Viagra can boost performance levels in certain sports.

The latest clinical study into the wonders of Viagra has now unearthed the possibility that its active ingredient may be utilised in the obesity epidemic that is particularly problematic here in the UK and the U.S. too.

Researchers from the University of Bonn and the Max Planck Institute for Heart and Lung Research in Germany were the ones who made the discovery, and now their findings may open up possibilities for the 500 million people around the globe who are classified as either overweight or obese.

Currently, many such people are turning to weight loss aids such as Alli, Xenical, and XLS-Medical, and the German study suggests that their predicament may have been prevented through sildenafil.
Like so many others do, the researchers used mice for study purposes and administered the ED medication to the mice for seven days and monitored the effect (if any) of their fat cells. Amazingly, it was found that the rodents appeared to be resistant to obesity even when fed a diet high in fat.

Sildenafil works by interfering with a signalling chain of the messenger cyclic guanosine monophosphate (cGMP), which allows the inflow of blood and an erection. Alexander Pfeifer, professor of pharmacology and toxicology at the University of Bonn, who led the study, commented why Viagra was chosen in the study, saying: “We have been researching the effect of cGMP on fat cells for quite some time now. This is why sildenafil was a potentially interesting candidate for us.”

Ana Kilic, Pfeifer’s colleague, spoke on their findings after the seven day period, saying: “The effects were quite amazing. Sildenafil increased the conversion of white fat cells, which are found in human ‘problem areas’, into beige ones in the animals. Beige fat cells burn the energy from ingested food and convert it to heat.” As these beige cells also ‘melt the fat’, researchers are now optimistic that Viagra could be used as a powerful weapon against obesity.

If white fat cells are continually getting ‘stuffed’ or experience a build-up of lipids, they become enlarged and can synthesize and release hormones which then results in inflammation and a higher risk of  developing chronic diseases.

These inflammatory responses then accelerate cardiovascular diseases. Heart attacks, strokes, cancer and diabetes are then likely following this. However, Pfeifer continued:  “It seems that sildenafil prevented the fat cells in these mice from getting onto that slippery slope.”

Travellers need strong vigilance against malaria and typhoid fever

In recent years more and more Brits have become fed up of the freezing cold temperatures over the winter season and many even decide to jet off to sunnier climates and areas such as the Tropics, where necessities to stave off the cold such as electric blankets, hot water bottles and a piping hot brew are simply not required!

Upon arriving back in the UK though, what would you do if you begin to feel unwell after a week or two of being back? In these instances, symptoms such as muscular aches/pains, diarrhoea, vomiting and a high temperature are commonly (and usually incorrectly) blamed on simple problems such as seasonal flu or food poisoning from out-of-date food or a dodgy takeaway meal. In fact, some of these symptoms are not too dis-similar to those suffered by over a million Brits recently with the norovirus epidemic which is still rife in many areas.

However, if you are feeling slightly under the weather after a visit to tropical regions such as West Africa, Southeast Asia, India, the Caribbean, etc., then it could be a cause for concern and something more serious than just a seasonal flu or food poisoning.

The findings of one particular study, published online yesterday in the American Journal of Tropical Medicine and Hygiene, have suggested that travel illnesses such as malaria and typhoid ought to be discussed with your GP following a visit to a tropical climate. In addition though, Medical Specialists Pharmacy strongly advise that these and many other travel illnesses such as traveller’s diarrhoea and dengue also be discussed, before travelling to your destination where there may be a high risk of such diseases.  To prevent contracting malaria, there are numerous antimalarial medications available from Medical Specialists for anybody visiting a country of risk. These include Doxycycline, Paludrine and Malarone – with the latter also able to treat the disease if you should get it.

University of Oslo researcher Mogens Jensenius, MD, PhD, and his team looked at the GeoSentinel surveillance network database to attain an incredible 15 years worth of information; this comprising of data contained on 82,825 returning travellers from Europe, North America, Israel, Japan, Australia and New Zealand. All had requested treatment for different health problems from June 1996 through to August 2011. It was ascertained that 4.4% (3,655) of these people had contracted either malaria, typhoid fever, or another type of deadly tropical disease. In total, 13 deaths were documented from the 3,655 patients and 10 of these were due to malaria.

Malaria was actually the most prevalent of the tropical diseases, seen in 76.9% of the diagnoses. The disease is caused by the Plasmodium parasite. The parasite is passed on to humans through the bites of infected female mosquitoes. Symptoms include muscular pain, headaches, diarrhoea, vomiting, severe sweats and chills and a fever of 38C (100.4F) or more.  

The second most common tropical disease was typhoid fever. Caused by the Salmonella typhi bacterium, it is an infection that may spread through the body after the person consumes food or water that has been contaminated with a small amount of infected faeces or urine. Symptoms include stomach pain and rashes in the first week of illness. During the second week, the sufferer will likely experience a worsening of symptoms that can include abdominal pain, weight loss and a fever that increases in temperature to about 39–40C (103–104F).

Both conditions are fatal without a prompt diagnosis and treatment; however those who contract malaria are more likely to die than those who contract typhoid fever, which can be treated in merely a few days with antibiotics.

Surprisingly, not one of the 80,000 had caught the often-fatal Ebola virus – one of the top-feared diseases in travellers due to its 90% fatality rate. ‘Ebola haemorrhagic fever’ as it is also known, occurs mainly via outbreaks within remote villages in Central and West Africa that are close to tropical rainforests.

Researcher Mogens Jensenius commented on the findings in the study, stressing just how serious the issue of tropical diseases is. He said: “While diagnosis and treatment of malaria and typhoid fever and many other tropical diseases have improved greatly over the years, people still can die from them if they are not treated quickly after their symptoms begin. Doctors and nurses in Western countries need to be vigilant in considering these potentially life-threatening tropical infections in recently-returned travellers with fevers, and identify and treat them quickly.”

Hospital blasted for proposed smoking shelter next to cancer ward

Bosses at The University of North Staffordshire hospital have caused a huge outpouring of anger after its plans to construct a smoking shelter outside a cancer ward were made public.

The hospital initially spoke of their proposed planning permission for five smoking shelters on-site in October of last year after staff, patients and visitors complained that smokers were repeatedly ignoring the rules regarding the strict no-smoking policy for directly outside the entrances to the hospital. However, further complaints were also made because of the fact that smokers would often convene in large groups on the A34, which is close by.

At the time, The hospital’s chief nurse Liz Rix said: “We want to encourage people not to smoke because of their health, but it’s become very difficult [to enforce the smoking ban].We have had so many complaints from staff, patients and visitors to the hospital about what you can see outside the grounds that we thought we had to try something different.” She also added that the hospital ‘absolutely do not condone’ smoking and would be ‘encouraging and supporting’ patients to stop smoking altogether.

If Stoke-on-Trent City Council give the go-ahead for the planning application (a decision is expected in February), then the five smoking shelters are to be erected next to two main entrances, the hospital’s maternity block, the accident and emergency unit and what has maybe caused the most fury – outside of the hospital’s cancer ward.

Cancer charities and people who have suffered with the deadly disease – commonly attributed to smoking – have now spoke out and blasted the prospect of a smoking shelter right beside a place where people are being treated for cancer, arguing it is a thoughtless and insensitive move from the hospital.

Cancer survivor Harry Larkins, 70, from Cheadle, Staffs, successfully managed to overcome cancer back in 2009 but still attends a check-up each year at the hospital. He hit out at the plans and said: “I know they have to accommodate smokers, but a lot of people in the cancer ward have smoked throughout their lives and don’t need reminding that could be the reason they are there. It’s just plain insensitive. It is a huge site and they could put them somewhere a lot more discreet. I think it’s a terrible error of judgement.”

Councillor Colin Eastwood, chairman of Newcastle Borough Council’s Health Scrutiny Committee, gave a scathing verdict of the hospital’s smoking shelters, saying: “I don’t feel the shelters are really addressing the problem of smoking. It is almost like condoning smoking. Smoking is a real issue in the local area and it concerns me that the hospital is providing for them. What they should be doing is supporting smokers who are admitted to hospital to quit the habit.”

To try and defend the plans, the chief nurse Lisa Rix commented: “We do not condone smoking on our premises by patients, visitors or staff. However, a degree of pragmatism has been adopted to keep the hospital clean and tidy and smokers away from building entrances. The beautiful main entrance has become a particular problem area with a large number of smokers congregating and at times it has been difficult to keep the area clean. We accept this has caused problems for neighbouring residential areas and are working with unions to see what actions can be taken to alleviate this. We enforce a blanket ban on staff smoking on our property and staff will not be allowed to use the shelters.”

Smoking is without doubt the most avoidable cause of many cancers and is often directly linked to throat, mouth, cervix, stomach, bowel and kidney cancer. The biggest killer though in regards to smoking-related cancers is lung cancer – responsible for over four out of every five cancer cases. Unfortunately lung cancer has one of the worst survival rates of any type of cancer but it is preventable with swift action that involves quitting smoking as soon as possible before it is too late.

Many people are able to give up smoking through the aid of the smoking cessation medication Champix, which works by replicating the effect of nicotine on the body. Therefore, it both reduces the urge to smoke and relieves withdrawal symptoms. Although you are not recommended to smoke after your quit date, Champix can also reduce the enjoyment of cigarettes if you do smoke when on treatment. It is available today from Medical Specialists Pharmacy from as little as just £75.00 per pack.

Impotence less likely for men dating women with slimmer waists

Slap-bang in the middle of January and obviously just after the typically indulgent Christmas period is never going to be the most ideal of times for anybody’s waistline as the struggle to lose the bulk gained from all that Christmas food and extra alcohol calories is still underway.

However, the results of a Scottish study on sexual dysfunction could provide some motivation for women to achieve that long-desired ‘figure 8’ body size – often associated as the pinnacle of feminine beauty. The study has possibly also shed light on the reasons why many men could desire women who boast a ‘waspish’ waist.

The results also linked the size and shape of a women’s waistline to the chances of satisfaction or the risk of her partner suffering from erectile dysfunction.

Researchers state that as humans have evolved over the years, our mind-set subconsciously correlates people who are overweight as having a much higher risk of having health problems. Ergo, men would usually perceive a woman who has a more slender waist to be in a healthier condition and an ideal mate for reproductive success.

The study included approximately 700 Czech men aged between 35 to 65 years of age and looked at how frequently they engaged in sexual intercourse. The researchers utilised the measuring scale known as the International Index of Erectile Dysfunction (IIEF)-15) to determine each man’s sexual function. The IIEF-15 is comprised of a set of 15 questions regarding erectile function and sexual satisfaction.

It was ascertained that the men who experienced less occurrences of male impotence were generally younger and had partners who were also younger in age, and interestingly partners who had a slimmer waist. In addition, the same men reported to being much more satisfied with their sex life.

Lead researcher Stuart Brody, professor of psychology at the University of West Scotland, shed some light on the apparent ‘waist effect’ seen in the study and highlighted that it was ‘noteworthy’ that those women who had a more slimmer waist were deemed to be more sexually appealing  in all measures of sexual function  – regardless of the age of each partner. One theory put forth for the findings in the study was that the abdominal body fat of the woman actually diminished their own desire on a hormonal level, negatively effecting libido. Whilst another reason was a little more straightforward and was that men could simply just find a more slender frame to be more attractive.

Mr Brody said: “The most compelling explanation was that slimmer women are, on average, more sexually attractive to men (resulting in more frequent sex, stronger erections, and greater satisfaction). This is not surprising, given evolutionary selection pressures, because accumulation of excess body fat, especially abdominally, is associated with elevated risk of metabolic, cardiovascular, and neoplastic disorders. The elevated risk of such disorders could result in poorer fitness and hence less desirability as a mating partner.”

Women are not the only ones though who need to begin counting the calories. It was also found by researchers that many of the men with larger waists reported a lower sexual satisfaction compared to their svelte counterparts. This may not come as a surprise though – Medical Specialists Pharmacy have previously touched upon the causes of erectile dysfunction and obesity has been found to be one of the leading causes of male impotence along with factors such as smoking, alcohol abuse and stress.

Coca-Cola tries to dispel obesity concerns with TV ads

Global Soft drinks giant Coca-Cola have gone to drastic measures to defend themselves against increasing concerns regarding the negative impact that fizzy drinks are having to our health. There is a staggeringly high sugar content in many drinks such as regular Coke, Pepsi, etc., and this is contributing towards tooth decay and the spiralling obesity epidemic occurring both in Britain and also in the U.S.

Interestingly, sales growth within North America over the last 15 years for Coca-Cola has directly emanated from millions of people deciding to go with the no-sugar and no-calorie options such as Coke Zero, clearly showing a huge public worry about the fuller-sugared versions. These diet versions of their soda drinks now comprise of roughly a third of its sales in the U.S. and Canada.

Therefore, to perhaps address the issue of obesity and attempt to alleviate the mounting pressure on the soft drinks industry, Coca-Cola have launched a new advertising campaign on cable television in the U.S. The two minute-long commercials were given their first airing during last night’s ‘The Situation Room with Wolf Blitzer’ on CNN, FOX News’ ‘The O’Reilly Factor’, and MSNBC’s ‘The Rachel Maddow Show’.

A spokeswoman for Coca-Cola, Diana Garza, said: “The audience for this new ad is knowledgeable about the problem but doesn’t necessarily know about what the Coca-Cola Co is doing to address it. We are telling them our story.” She also acknowledged that the company had to try and remain consistent with its brand voice and avoid sounding ‘preachy’.

In the advert shown on Monday night, a female voice was heard stating that Coca-Cola drinks actually have reduced portion sizes in the form of smaller cans, the company are putting their efforts into creating better-tasting, low-calorie sweeteners and has voluntarily made lower-calorie drinks available at schools. Viewers are also provided with a reminder that ‘all calories count no matter where they come from’ and ‘if you eat and drink more calories than you burn off, you’ll gain weight’.

The advertisements are also expected during many other shows tonight too and a separate commercial, explaining about Coke’s front-of-package calorie labels, will be screened for the first time Wednesday during ‘American Idol’ on Fox – who have partnered with Coke for several years.

The second ad is a stark contrast to the first, and could be seen as more traditionally ‘upbeat’ as people would expect from company known for their series of happy Christmas television adverts. It will feature a montage of fun activities that will equate to burning off the ‘140 happy calories’ contained in a can of Coke: dancing, laughing with friends, walking a dog and doing a victory dance after getting a strike during a game of bowling.

However, Coca-Cola claims that their new series of videos have not been created due to mainstream bashing of the soft drink industry, but as a way to ‘raise awareness’.

The campaign follows tough action by news that US government officials are specifically concentrating on high-calorie soft drinks for stricter regulations. In New York, a city where shockingly 58% of people are classed as either overweight or obese, a new law will come into effect from March barring the sale of soft drinks larger than a pint in any cinema, restaurant and stadia.

Unfortunately it seems that not everybody agrees with the real intentions of Coca-Cola’s television campaign. Michael Jacobson, executive director of the Center for Science in the Public Interest, has long been critical of the soft drinks industry, and he said that the move “looks like a page out of Damage Control 101. They’re trying to disarm the public.” However, Mr Jacobson did not stop there in his scathing assessment and added: “They’re trying to pretend they’re part of the solution instead of part of the problem. If Coke was serious about wanting to be part of the solution, it could stop advertising full-calorie drinks altogether, set up a pricing scheme where full-calorie drinks were more expensive, or stop opposing proposed soda taxes.”

Junk food contributing to health problems in kids

There are countless health problems that junk food can pose to children. As well as being terrible for skin, causing spots and maybe losing popularity with friends, junk food can contribute towards tooth decay, is primarily responsible for the increasing childhood obesity epidemic that is sweeping across Britain – now being thought to increase the risk of liver disease in children and even leading to experts designing a childhood obesity risk calculator which can predict a new-born’s chance of becoming obese as they get older.

However, thanks to a study conducted by researchers based at New Zealand’s Auckland University, the list of health problems in kids that can be attributed to the consumption of junk food can now be increased.

More specifically, they are coincidentally the same issues that a survey published last week found could possibly be connected to the failure of Brits to wash their bed sheets at least once every week – asthma, eczema and rhinitis.

The study was a project examining the dietary habits of 181,000 youngsters aged six to seven within 31 different countries, in addition to 319,000 teenagers aged 13-14 from 51 countries.
Both the kids and their parents were given questions regarding the youngster’s diets and if the kids suffered from symptoms of asthma, or had itchy eyes, runny noses and eczema – a skin condition that causes itching and red/dry skin that can be appear cracked or broken.

From the results of the Auckland University study, health experts are now concerned that a diet comprising of high levels of saturated fat can be detrimental to children’s immune systems. This is because it was discovered that teenagers who ate food such as burgers three times a week or more were at a 39% higher risk of developing severe asthma, whilst younger kids were found to be 27% more at risk.  In fact, regardless of gender or financial status, junk food was the only type of food to show similar health problems across both age groups.

Those who ate junk food at least three times each week were also more susceptible to the eye condition rhinoconjunctivitis (rhinitis) – characterised by various symptoms including sneezing, red eyes,  runny nose and nasal congestion. However, the researchers also learned that by consuming about three portions of fruit and veg each week could reduce the risk by 14% in the younger group and 11% for the teenagers.

Writing in the British Medical Journal, the study authors state that their findings do not prove a definite cause and effect, but comment: “Fast food may be contributing to increasing asthma, rhinoconjunctivitis and eczema. Regular consumption of fruit and vegetables is likely to protect against these diseases.”

If you have suffering with Allergic rhinitis and/or asthma then Medical Specialists are at hand to help. We have a vast range of medications to help both asthma and allergy sufferers, all at fantastic prices. If you are suffering from asthma-like symptoms, you should see your doctor immediately for a diagnosis.

Your doctor is able to prescribe medication if he feels you have asthma. If you have already been prescribed an inhaler or have lost your inhaler or run out and cannot get a prescription immediately, we are able to supply you an inhaler to help your asthma symptoms. We have both blue (relievers) inhalers such as Ventolin and Salbutamol, and brown (preventers) inhalers such as Qvar Beclomethasone and Qvar Easi-Breathe.

If you suffer from hay fever or allergies we have many options for you including Alomide allergy eye drops, Loratadine tablets, Nasonex spray, Prevalin allergy nasal spray and Prevalin allergy kids nasal spray.

Anger at hospital patients being denied the latest treatments

A new report commissioned by the Department of Health (DoH) paints a damning picture of the NHS’ priorities and procedures, showing that they are inexplicably not prescribing the latest and most effective medications for bowel, brain, lung and ovarian cancer that have been previously given the green-light by NHS watchdog National Institute for Health and Clinical Excellence (NICE). The report details how often treatments approved by NICE are being prescribed by hospitals and GPs.

Some of the new treatments have incredibly prolonged the lives of terminally ill patients by over a year in some cases whilst others managed to improve the survival rates of patients by roughly a quarter, so the news that the drugs are not being utilised will no doubt infuriate families across the UK.

The same DoH report also documents how numerous hospitals are seemingly refusing to prescribe the most up-to-date treatments for other health conditions such as arthritis, asthma, Crohn’s Disease, heart attacks and multiple sclerosis.

It would also seem certain patients would benefit over others luckily by circumstance as some hospitals have been routinely prescribing the latest drugs for several years compared to others who have not bothered at all and sticking to oldest ‘tried and tested’ treatments, regardless of if there is anything potentially more effective for the patient.

Ministers and charities have blasted the findings of the DoH, saying it is ‘completely unacceptable’ that the new drugs have been held back for so long – some being approved by NICE seven years ago – and that hospital patients are being denied access to treatment that could significantly improve symptoms and even extend their life.

Specific reasons for the refusal of many hospitals to offer the new treatments to patients can be only speculation until answers are demanded from the government, but some believe it may be because doctors are cautious to prescribe drugs they are not fully familiar with and will instead remain with treatments they have trusted over the years.

Health Minister Lord Howe reacted angrily to the news and said: “Patients have a right to medicines and treatments that have been approved by NICE and are clinically appropriate for them, and it is completely unacceptable if this is not happening. We are determined to drive out unjustified variation.”

Adding to Lord Howe’s comments was Andrew Wilson, Chief Executive of the Rarer Cancers Foundation, who said: “NICE was meant to end the postcode lottery but these figures show that it is alive and well. Access to drugs should not depend on where you live or in which hospital you are treated.”

Although health officials protest that the information contained in the report is ‘experimental’ and too early to draw conclusions, some facts are plain to see and include the staggering news that a drug for advanced bowel cancer has not been utilised at any time by at least 25 hospital trusts – despite receiving NICE approval way back in 2006.

Other findings show that 15 trusts are spurning the opportunity to provide the drug Erlonitib to lung cancer patients. It works at preventing the development of tumours for approximately a year and was approved by NICE in 2008.

However, it gets worse – it has been discovered that there are 24 trusts around to country who are not offering the drug Paclitaxel to women with advanced ovarian cancer. If they had the medication, it could extend their lifespan by an additional year.

Katherine Murphy, chief executive of the Patients Association, also gave her opinion on the subject, saying: “Patients have the right to drugs and treatments that have been recommended by NICE for use in the NHS, if their doctor says they are clinically appropriate. Any perception that there is a rationing of NICE approved medication taking place at a local level is a real concern.”