People usually wear plasters to stem blood flow, but imagine putting one on to actually get something into the bloodstream?
For that is the idea behind a new way to treat erectile dysfunction in men, with scientists at universities at Cairo and Saudi Arabia looking at getting viagra into the blood, acting in a similar way to a smoking patch.
Men suffering with impotence problems
would theoretically be able to wear the viagra skin patch on their upper
arm or the abdomen, and perhaps most importantly for men, will kick-in
within just a matter of seconds or minutes. Viagra can take between 30
minutes to an hour to work.
This means it will get men in the mood for sex even quicker than the
time it takes them to get into the bedroom and take their clothes off!
Moreover, after taking the tablet version of viagra, some men
occasionally experience various non-life threatening side effects such
as blurred vision, slight headache, indigestion and muscle pain. The new
erectile dysfunction skin patch would mean an end to these unwanted
effects.
The team involved in the research at King Abdulaziz University in
Jeddah, Saudi Arabia, along with scientists at Cairo University,
utilised a new drug delivery method, known as transferome technology.
A tiny patch measured at just 1cm squared was created, comprised of
minute particles of sildenafil citrate (the active ingredient in viagra)
which is coated with thin layers of fat and chemicals that will enable
the skin to absorb the drug.
The patch was then tested on rats in order to judge just how much –
if any – of the medicine would manage to penetrate the skin. The patch
used on the rats only contained 1 milligram of viagra, which means
bigger patches would need to be fashioned to accommodate for doses of
viagra prescribed to men, which can range from 25mg to 100mg.
In a report in the journal Drug Design, Development and Therapy,
scientists said the results demonstrated that viagra particles
successfully transmitted through both the outer and inner layers of the
skin.
In a report on the findings they said: “This could be a promising delivery system for the drug.
“The skin is an alternative route to the oral one, prolonging the effect and reducing variability.”
Although the patch has only been tested on rats thus far, there are hopes for future clinical trials on humans.
Since viagra first became available in 1998, its popularity has
skyrocketed and has boosted the love lives of millions of men across the
globe. After viagra became a huge success, its chunk of the market was
somewhat reduced following the 2003 FDA-approvals of both levitra
(vardenafil) and cialis (tadalafil) for the treatment of erectile dysfunction.
According to official health statistics, over 3.5m prescriptions were
dispensed in England during 2015 alone for medicines to treat erectile
dysfunction.
The manufacturers of viagra, Pfizer, were forced into lowering the
hefty price of viagra after seeing its patent expire in 2013 and this
led to many generic sildenafil
products entering the market, drugs that contained exactly the same
active ingredient of the branded viagra, but could be sold to patients
for just a fraction of the price.
However, men might not want to completely ditch their oral
medications just yet. The British Society of Sexual Medicine’s Dr Geoff
Hackett warns that the patches will actually hit patients hard in the
wallet compared to existing treatments.
“It might be a nice way of delivering the drug,” he said.
“But I can’t see how a patch likely to cost around £10 is going to replace a pill that’s a fraction of the price.”
No comments:
Post a Comment