A research team at the Universitat Autonoma de Barcelona in Spain have produced compelling evidence that Sildenafil, the ingrediant in the erectile dysfunction drug Viagra, could be used to reduce the symptoms of multiple sclerosis (MS).
The findings of their study have been published in the journal Acta Neuropathologica. They demonstrate, in an animal model of multiple sclerosis, that daily treatment with sildenafil quickly reduces the symptons of the disease, with a near complete recovery in 50% of the cases after eight days of treatment.
MS is a chronic inflammatory disease of the central nervous system in which the fatty myelin sheaths around the axons of the brain and spinal cord are damaged, leading to demyelination and scarring.
Symptoms include changes in sensation, muscle weakness, abnormal muscle spasms, difficulties with moving, coordination and balance, and problems in speech, swallowing and vision. The symptoms often appear in episodic acute periods of worsening, known as relapses, or in a gradually progressive deterioration of neurologic function.
MS is one of the main causes of disability in young adults, and while there is currently no cure, some medicines and treatments attempt to return function after attacks or prevent attacks.
In their study, the researchers observed that the medication reduced the infiltration of inflammatory cells into the white matter of the spinal cord, lessening damage to the nerve cell’s axon and facilitating myelin repair.
The researchers are confident that clinical trials with human patients will be soon carried out, given that the drug is widely tolerated and has already been used for treatment of erectile dysfunction in MS sufferers.
Tuesday, 31 May 2011
Are Diet Pills An Easy Option?
Statistics recently issued show a significant increase in overweight men and women resorting to diet pills, in a bid to lose their excess weight.
Due to obesity rising from 7% of adults in 1980 to 23% in 2009 doctors are issuing up to 15 million prescriptions a year for diet drugs.
After findings of various side effects caused by the different drugs that were available many have now been withdrawn from the market, leaving Xenical as the only anti-obesity drug that is available on prescription.
It is feared that doctors are issuing the drugs as a quick fix instead of focusing on healthy eating and exercise, this is strongly argued by doctors that issuing an anti-obesity drug is a last resort to overweight adults when a change of diet and lifestyle has failed.
Usage of Xenical does allow the taker to lose weight at a greater rate than simply through exercise and healthy living, however, it is important to stress that to have a positive impact on weight loss patients must adopt healthier eating habits and undertake exercise. This should lead to long term weight loss and also help to reduce some of the possible side effects such as bowel movement problems.
Due to obesity rising from 7% of adults in 1980 to 23% in 2009 doctors are issuing up to 15 million prescriptions a year for diet drugs.
After findings of various side effects caused by the different drugs that were available many have now been withdrawn from the market, leaving Xenical as the only anti-obesity drug that is available on prescription.
It is feared that doctors are issuing the drugs as a quick fix instead of focusing on healthy eating and exercise, this is strongly argued by doctors that issuing an anti-obesity drug is a last resort to overweight adults when a change of diet and lifestyle has failed.
Usage of Xenical does allow the taker to lose weight at a greater rate than simply through exercise and healthy living, however, it is important to stress that to have a positive impact on weight loss patients must adopt healthier eating habits and undertake exercise. This should lead to long term weight loss and also help to reduce some of the possible side effects such as bowel movement problems.
Friday, 1 April 2011
Ginseng and Saffron May boost your Libido
Adding ginseng and saffron to your daily diet could boost up your libido say Scientists. Experts found the plant extracts helped to boost performance in bed. They looked at hundreds of aphrodisiac studies that included claims of mental and physical enhancement.
Prof Massimo Marcone, of the University of Guelph, Canada, said: “Aphrodisiacs have been used for thousands of years around the world. “But the science behind the claims has never been well understood or clearly reported. Ours is the most thorough review to date.”
But before you run to the shops to buy ginseng or saffron, the experts said more research was needed. They also found prescription medication such as Viagra, Cialis & Levitra, despite helping erectile dysfunction, did not increase libido. And booze made people feel frisky but impeded performance. And, disappointingly, chocolate was not linked to arousal or satisfaction.
Prof Massimo Marcone, of the University of Guelph, Canada, said: “Aphrodisiacs have been used for thousands of years around the world. “But the science behind the claims has never been well understood or clearly reported. Ours is the most thorough review to date.”
But before you run to the shops to buy ginseng or saffron, the experts said more research was needed. They also found prescription medication such as Viagra, Cialis & Levitra, despite helping erectile dysfunction, did not increase libido. And booze made people feel frisky but impeded performance. And, disappointingly, chocolate was not linked to arousal or satisfaction.
Wednesday, 30 March 2011
Drug dealer spared jail by soft judge
Colin MacDonald, 34, appeared for sentencing before Judge Stephen Holt after cops who raided his home found:
90g of highly-addictive crystal meth rocks stuffed in a washbag;
90g of powdered cocaine;
100 ecstasy pills;
85g of amphetamines, and THREE bin bags stuffed with dried cannabis leaves.
Police also discovered seven boxes of Viagra, a large quantity of powerful painkiller Tramadol, self-seal bags and two sets of scales. MacDonald admitted five counts of possession with intent to supply Class A and Class B drugs at a magistrates' hearing. Yet Judge Holt gave him just a suspended 12-month jail term.
And MacDonald, of Dollis Hill, North London, walked free.
Source:http://www.thesun.co.uk/sol/homepage/news/3499088/Judge-lets-off-pusher-with-50k-drug-haul-including-crystal-meth.html?OTC-RSS&ATTR=News
90g of highly-addictive crystal meth rocks stuffed in a washbag;
90g of powdered cocaine;
100 ecstasy pills;
85g of amphetamines, and THREE bin bags stuffed with dried cannabis leaves.
Police also discovered seven boxes of Viagra, a large quantity of powerful painkiller Tramadol, self-seal bags and two sets of scales. MacDonald admitted five counts of possession with intent to supply Class A and Class B drugs at a magistrates' hearing. Yet Judge Holt gave him just a suspended 12-month jail term.
And MacDonald, of Dollis Hill, North London, walked free.
Source:http://www.thesun.co.uk/sol/homepage/news/3499088/Judge-lets-off-pusher-with-50k-drug-haul-including-crystal-meth.html?OTC-RSS&ATTR=News
Tuesday, 29 March 2011
Viagra turns thirteen
27th March this day in 1998, the Food and Drug Administration (FDA) approved the drug Viagra, Later that year; it was approved for sale on the European market by the European Commission.
The main ingredient of Viagra – the chemical sildenafil – was initially being trialled as a treatment for angina. But researchers at Pfizer soon found that, while sildenafil had nominal effect on angina patients, it was highly effective at inducing erections. The reaction took about an hour, a little longer if the pill was taken after eating fatty foods. Seeing the economic opportunity in such a biochemical effect, Pfizer decided to market the drug for male impotence also know as erectile dysfunction.
When Viagra was first marketed, erectile dysfunction was a condition that was under-recognised by most members of the public. So in order to increase awareness, Pfizer recruited ex-US Presidential candidate Bob Dole to act as a spokesperson for Viagra in advertisements. This post would later also be filled by the Brazilian football legend Pele.
The popularity of Viagra would eventually inspire Pfizer’s competitors to create their own erectile dysfunction treatments. The first of these to be approved was Levitra, which was co-marketed by GlaxoSmithKline (GSK), Bayer and Schering-Plough in August 2003. In October 2003 another erectile dysfunction medication called Cialis, marketed by GSK, was approved.
All three erectile dysfunction medications have been used by millions of men worldwide. Viagra sales in 2010 alone were around $1.9 billion. Next year Pfizer will face an important milestone – the expiration of Viagra’s American patent. In parts of the world where Viagra does not have a valid patent, such as China, genetic versions of Viagra are already available under names such as Kamagra and Caverta. Once the US patent is up (providing Pfizer is unable to obtain an extension), generic versions of Viagra may begin to become a significant rival to the branded drug.
Wednesday, 23 March 2011
New levitra dissolvable tablets now on sale in the UK
Bayer have released a new dissolvable erectile dysfunction tablet called Levitra ODT (Orodispersible). This is a new type of pill that melts in your mouth to treat male impotence which introduced in the UK yesterday.
Bayers researchers are hoping it will help men who feel too embarrassed to seek help for erectile dysfunction, as it can be taken quickly at the patient’s discretion. Called Levitra orodispersible, it is manufactured by Bayer.
“It is hoped the advantages of the new product and its discreet packaging will reduce the numbers of patients purchasing counterfeit pills online,” said Marc van Unen of Bayer. Men should still take this drug 30 minutes before sexual intercourse.
Market research by Bayer, makers of the new pill, found four in ten men say existing tablets, which have to be swallowed with water, are inconvenient.
Trials involving almost 1,000 men found the melt-in-the-mouth treatment was safe and effective.
Sexual health campaigners warn that those with erectile dysfunction should always see a doctor because it could suggest the early stages of heart problems.
But many have ended up buying fake products online because they are too shy to see their GP.
Levitra ODT works like Viagra – fizzes on the tongue and dissolves in seconds, meaning it can be taken very discreetly. Levitra is available at Medical Specialists Pharmacy website via private prescription or through our online consultation..
For further information on Levitra dissolvable tablets please visit Medical Specialists Pharmacy website, and for where to Buy Levitra ODT please click the highlighted link.
Friday, 18 March 2011
Pfizer to sell new chewable Viagra in Mexico
Mexican men who have difficulty swallowing Viagra tablets will soon be able to have a chewable version of Viagra. It is known as Viagra Jet, and was developed over four years in Mexico, where Pfizer will start selling it on March 21.
The U.S. pharmaceutical company said on Thursday that the chewable form of the 13-year-old tablet was developed in response to studies of the Mexican market, which is Viagra‘s biggest in Latin America after Brazil.
“It’s a new alternative for patients and doctors,” said Beatriz Romero, Pfizer’s marketing manager in Mexico. “The chewable format could appeal to patients, particularly those who can’t swallow the tablets.”
Pfizer said studies have shown that as many as 60 percent of people grind tablets or open capsules to make the contents easier to ingest. About 6 million Mexican men suffer from impotence, according to a 2001 study published in the medical journal Revista Mexicana Urologia. Pfizer said it estimates that 1 million of them receive treatment.
Pfizer has reported that it sells around 3 million Viagra pills a year in Mexico alone. According to research firm IMS Health, Viagra has about one third of the market share in Latin America’s second biggest economy.
Viagra Jet is only available in Mexico, but the company may introduce it to other Latin American countries, depending upon local regulatory approval, Pfizer spokeswoman Karla Fuentes said.
The development of Viagra Jet will not extend the drug’s patent life beyond its 2012 expiration, Pfizer said. A number of the company’s patents are due to expire over the next few years, and it has said that it would drastically reduce its research budget to shrink operations.
The U.S. pharmaceutical company said on Thursday that the chewable form of the 13-year-old tablet was developed in response to studies of the Mexican market, which is Viagra‘s biggest in Latin America after Brazil.
“It’s a new alternative for patients and doctors,” said Beatriz Romero, Pfizer’s marketing manager in Mexico. “The chewable format could appeal to patients, particularly those who can’t swallow the tablets.”
Pfizer said studies have shown that as many as 60 percent of people grind tablets or open capsules to make the contents easier to ingest. About 6 million Mexican men suffer from impotence, according to a 2001 study published in the medical journal Revista Mexicana Urologia. Pfizer said it estimates that 1 million of them receive treatment.
Pfizer has reported that it sells around 3 million Viagra pills a year in Mexico alone. According to research firm IMS Health, Viagra has about one third of the market share in Latin America’s second biggest economy.
Viagra Jet is only available in Mexico, but the company may introduce it to other Latin American countries, depending upon local regulatory approval, Pfizer spokeswoman Karla Fuentes said.
The development of Viagra Jet will not extend the drug’s patent life beyond its 2012 expiration, Pfizer said. A number of the company’s patents are due to expire over the next few years, and it has said that it would drastically reduce its research budget to shrink operations.
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